Development and Formulation of the Experimental Dentifrice Based on Passiflora mollissima (Tumbo) with and without Fluoride Anion: Antibacterial Activity on Seven Antimicrobial Strains
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Fecha
2019Autor(es)
Mayta-Tovalino, Frank
Gamboa, Eloy
Sánchez, Richard
Rios, Jorge
Medina, Ramín
García, Martín
Asencios, Jhonn
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Objectives. To develop and formulate a new experimental dentifrice with and without fluoride based on the peel and the fruit of the
Passiflora mollissima (tumbo) and also to evaluate its antimicrobial activity against seven bacterial strains. Methods. )e sample
was calculated using the mean comparison formula, obtaining wells (n = 12) for each of the strains evaluated: S. mutans, E. faecalis,
Actinomyces, Lactobacillus, C. albicans, S. sanguinis, and S. oralis. )e antibacterial activity of the dentifrice was evaluated by the
direct contact technique. Results. It was found that the highest antimicrobial activity was only present in pulp-based dentifrices
against strains of S. mutans 21.0 ± 1.8, E. faecalis 16.3 ± 3.9, Actinomyces 22.1 ± 1.3, and Lactobacillus 21.0 ± 1.3. However, in
comparison with other strains such as C. albicans, S. sanguinis, and S. oralis, the peel-based dendrifrice of Passiflora mollissima
obtained the highest antimicrobial activity. Conclusion. )e experimental dentifrice based on Passiflora mollissima had an
antibacterial effect against the seven microbial strains during the first 24 and 48 hours.
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