Listar Publicaciones indizadas por autor "Bravo, Leny"
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Effect of CCL5 expression in the recruitment of immune cells in triple negative breast cancer
Bravo, Leny (Scientific Reports, 2018)Acceso abiertoTriple negative breast cancer (TNBC) is the most aggressive form of breast cancer with limited options of targeted therapy. Recent findings suggest that the clinical course of TNBC may be modified by the presence of ... -
In silico evaluation of DNA Damage Inducible Transcript 4 gene (DDIT4) as prognostic biomarker in several malignancies
Bravo, Leny; Fajardo, Williams (Scientific Reports, 2017)Acceso abiertoDDIT4 gene encodes a protein whose main action is to inhibit mTOR under stress conditions whilst several in vitro studies indicate that its expression favors cancer progression. We have previously described that DDIT4 ... -
Patterns of Mutation Enrichment in Metastatic Triple-Negative Breast Cancer
Saravia, César H.; Bravo, Leny; Zavaleta, Jenny (Clinical Medicine Insights: Oncology, 2019)Acceso abiertoBackground: Triple-negative breast cancer (TNBC) is a heterogeneous disease with aggressive biology and complex tumor evolution. Our purpose was to identify enrichment patterns of genomic alterations in metastatic ... -
Precision medicine for locally advanced breast cancer: frontiers and challenges in Latin America
Casas, Alberto; Bravo, Leny; Zavaleta, Jenny (ecancer, 2019)Acceso abiertoAdvances in high-throughput technologies and their involvement in the ‘omics’ of cancer have made possible the identification of hundreds of biomarkers and the development of predictive and prognostic platforms that model ...