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Patterns of Mutation Enrichment in Metastatic Triple-Negative Breast Cancer
(Clinical Medicine Insights: Oncology, 2019)
Background: Triple-negative breast cancer (TNBC) is a heterogeneous disease with aggressive biology and complex tumor evolution.
Our purpose was to identify enrichment patterns of genomic alterations in metastatic ...
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Effect of CCL5 expression in the recruitment of immune cells in triple negative breast cancer
(Scientific Reports, 2018)
Triple negative breast cancer (TNBC) is the most aggressive form of breast cancer with limited options
of targeted therapy. Recent findings suggest that the clinical course of TNBC may be modified by the
presence of ...
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In silico evaluation of DNA Damage Inducible Transcript 4 gene (DDIT4) as prognostic biomarker in several malignancies
(Scientific Reports, 2017)
DDIT4 gene encodes a protein whose main action is to inhibit mTOR under stress conditions whilst
several in vitro studies indicate that its expression favors cancer progression. We have previously
described that DDIT4 ...
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Precision medicine for locally advanced breast cancer: frontiers and challenges in Latin America
(ecancer, 2019)
Advances in high-throughput technologies and their involvement in the ‘omics’ of cancer have made possible the identification of hundreds of
biomarkers and the development of predictive and prognostic platforms that model ...
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