Level of knowledge about metalloproteinases in dental students close to graduate from three universities in Peruvian capital city
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Date
2021-12-19Author(s)
Cayo-Rojas1, César Félix
Soto-Castro2, Lilliam
Castro-Mena1, Manuel
Medrano-Colmenares3, Sara
López-Gurreonero4, Carlos
Córdova-Limaylla1, Nancy C
Briceño-Vergel1, Gissela
Ladera-Castañeda1, Marysela3
Cervantes-Ganoza2, Luis
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Abstract
Background: Metalloproteinases are proteolytic enzymes that degrade dentin and
periodontal collagen; therefore, it is of special interest that dental students know its
mechanism of action and how its effects can be inhibited. Therefore, the aim of this
research was to evaluate the level of knowledge about metalloproteinases in dental
students close to graduate from three universities in Peruvian capital city.
Materials and methods: In this analytical, observational, cross-sectional and prospec tive study, 223 dental students close to graduate in three Peruvian universities were
evaluated from September to November 2020. A questionnaire of 20 closed questions
with three answers was validated and used to measure the level of general and dental
knowledge about metalloproteinases. A logit model was used to evaluate the influence
of the following variables: “gender” (X1), “type of university” (X2), “marital status” (X3)
and “age group” (X4), in the knowledge levels of the students, considering a p-value <.05.
Results: Of the 223 dentistry students, it was obtained that the level of knowledge
about metalloproteinases was predominantly low with 82.1%, (95% confidence inter val (CI): 77.1%–87.1%) of the total. According to multivariate logistic regression analy sis, "type of university" was the only variable that proved to have a significant influence
(p = .022) on the level of knowledge about metalloproteinases with an odds ratio of
(OR = 0.44; CI: 0.21–0.89), whilst the other variables "age group" (p > .05), "gender"
(p = .058) and "marital status" (p = .114) were not considered influential factors.
Conclusion: The majority of final year dental students in three Peruvian universities
presented a low level of overall knowledge about metalloproteinases. In addition, pri vate university students were 56% less likely to pass the subject knowledge test. On
contrary, gender, age group and marital status did not significantly influence the level
of knowledge of the students.
KEYWORDS
dental students, dentistry, knowledge, metalloproteinase inhibitors, metalloproteinases, Peru
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