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DNA Damage inducible Transcript 4 Gene: The Switch of the Metabolism as Potential Target in Cancer
(Frontiers in Oncology, 2018)
DNA damage inducible transcript 4 (DDIT4) gene is expressed under stress situations
turning off the metabolic activity triggered by the mammalian target of rapamycin (mTOR).
Several in vitro and in vivo works have ...
Acceso abierto
Effect of CCL5 expression in the recruitment of immune cells in triple negative breast cancer
(Scientific Reports, 2018)
Triple negative breast cancer (TNBC) is the most aggressive form of breast cancer with limited options
of targeted therapy. Recent findings suggest that the clinical course of TNBC may be modified by the
presence of ...
Acceso abierto
Clinicopathological predictors of long-term benefit in breast cancer treated with neoadjuvant chemotherapy
(World Journal of Clinical Oncology, 2018)
AIM
To investigate the survival impact of clinicopathological
factors, including pathological complete response
(pCR) and tumor-infiltrating lymphocytes (sTIL) levels
according to subtypes, in breast cancer (BC) ...
Acceso abierto
Factors associated with depression in patients with Parkinson’s disease, A multicenter study in Lima, Peru
(Dement Neuropsychol, 2018)
The diagnosis and treatment of depression in patients with Parkinson’s disease (PD) is inadequate, often
contributing to a reduced quality of life, rapid disease progression, higher cognitive impairment, and an increased ...
Acceso abierto
MGMT promoter methylation in Peruvian patients with glioblastoma
(ecancer, 2018)
Purpose: O6 -methylguanine–DNA methyltransferase (MGMT) promoter methylation predicts the outcome and response to alkylating
chemotherapy in glioblastoma. The aim of this study is to evaluate the prevalence of MGMT ...
Acceso abierto
Distribution of tumor-infiltrating immune cells in glioblastoma
(CNS Oncology, 2018)
Aim: Evaluation of features related to infiltrating immune cell level in glioblastoma. Methods: Tumor-
infiltrating lymphocytes (TILs) through H&E staining, and TILs (CD3, CD4, CD8 and CD20) and macrophage
(CD68 and ...
Acceso abierto